{"stable_id":"1f75e0019e001676","slug":"tempus-time-trial-activation","company":"Tempus AI TIME / TriHealth Cancer Institute","workflow_name":"Population-scale matching with rapid activation","function_code":"healthcare_screening","pattern_codes":["creator_to_judge"],"changed_assumption":"Continuous population screening can connect eligible patients to a standardized activation lane.","evidence_strength":"verified","publication_tier":"showcase","freshness":"current","reviewed_at":"2026-08-23","updated_at":"2026-08-22","source_quality_summary":"1 independent; publication outcomes are verified.","caveat_summary":"Journal of Clinical Oncology conference supplement abstract, not a full peer-reviewed article; nonrandomized comparison and bundled operating-model change.","freshness_caveat":null,"workflow_summary":{"before":[{"actor":"TriHealth research staff","action":"Screens available patients against non-TIME trial criteria and confirms possible eligibility.","actor_type":"human"},{"actor":"Site contracts and IRB teams","action":"Negotiate trial terms and complete conventional activation.","actor_type":"control"}],"hinge":"Continuous population screening can connect eligible patients to a standardized activation lane.","after":[{"actor":"TApp","action":"Re-runs eligibility searches when patient data or trial criteria change and produces candidate matches.","actor_type":"system"},{"actor":"Tempus nurse and TriHealth staff","action":"Nurse reviews algorithmic matches; site staff perform confirmatory screening before consent.","actor_type":"human"}],"decision_mode":"shared","decision_marker":"Human moves from creator to judge"},"before":[{"order":1,"actor":"TriHealth research staff","action":"Screens available patients against non-TIME trial criteria and confirms possible eligibility.","handoff_to":"Investigator and activation team","control":"Human clinical confirmation; the comparison reports 186-day non-TIME activation but not each queue stage."},{"order":2,"actor":"Site contracts and IRB teams","action":"Negotiate trial terms and complete conventional activation.","handoff_to":"Open trial and consent workflow","control":"Site, sponsor and IRB approvals remain required."}],"after":[{"order":1,"actor":"TApp","action":"Re-runs eligibility searches when patient data or trial criteria change and produces candidate matches.","handoff_to":"Tempus nurse review queue","control":"NLP match only; site capability and recency filters bound the queue."},{"order":2,"actor":"Tempus nurse and TriHealth staff","action":"Nurse reviews algorithmic matches; site staff perform confirmatory screening before consent.","handoff_to":"Standardized activation lane","control":"Pre-negotiated rate card/agreement and central IRB are bundled with AI; patient consent remains human."}],"decision_rights":"Humans confirm eligibility and consent; AI only proposes candidates.","exception_path":"Filtered or clinically ineligible matches are discarded.","removed_work":["Manual first-pass population search"],"outcomes":[{"metric":"Trial activation time","baseline":"186 days non-TIME","result":"37 days TIME; 80% reduction","period":"2022-01 to 2023-03","scale":"18,823 patients; 135 trials; 8.65 million searches","attribution_caveat":"Journal of Clinical Oncology conference supplement abstract, not a full peer-reviewed article; nonrandomized comparison and bundled operating-model change.","evidence_label":"verified"}],"executive_lesson":"The unit is a human-confirmed match connected to a pre-negotiated activation lane.","anti_pattern":"Do not attribute bundled contracting gains solely to AI.","questions_for_leaders":["Where is the operating threshold set and who can override it?","What measured result would trigger rollback or retraining?","Which residual decisions must remain human-owned?"],"collections":["regulated-autonomy"],"bundle_version":"1.0.0","bundle_fingerprint":"sha256:c23c6cc2b88153d008ea8fda928f632ce0011fc2d4c5036672a16e5d895bab93","canonical_url":"https://brianletort.ai/transformations/tempus-time-trial-activation"}