---
title: >-
  Tempus AI TIME / TriHealth Cancer Institute: Population-scale matching with rapid
  activation
slug: tempus-time-trial-activation
stable_id: 1f75e0019e001676
company: Tempus AI TIME / TriHealth Cancer Institute
function_code: healthcare_screening
pattern_codes:
  - creator_to_judge
evidence_strength: verified
publication_tier: showcase
freshness: current
reviewed_at: '2026-08-23'
updated_at: '2026-08-22'
source_quality_summary: 1 independent; publication outcomes are verified.
caveat_summary: >-
  Journal of Clinical Oncology conference supplement abstract, not a full peer-reviewed
  article; nonrandomized comparison and bundled operating-model change.
collections:
  - regulated-autonomy
bundle_version: 1.0.0
bundle_fingerprint: sha256:c23c6cc2b88153d008ea8fda928f632ce0011fc2d4c5036672a16e5d895bab93
canonical_url: https://brianletort.ai/transformations/tempus-time-trial-activation
---

# Tempus AI TIME / TriHealth Cancer Institute: Population-scale matching with rapid activation

Continuous population screening can connect eligible patients to a standardized activation lane.

Function: Healthcare screening. Patterns: Creator to judge. Evidence: verified.

Freshness: current. Reviewed: 2026-08-23. Updated: 2026-08-22.


Source quality: 1 independent; publication outcomes are verified.

## Before

1. **TriHealth research staff** — Screens available patients against non-TIME trial criteria and confirms possible eligibility. (control: Human clinical confirmation; the comparison reports 186-day non-TIME activation but not each queue stage.)
2. **Site contracts and IRB teams** — Negotiate trial terms and complete conventional activation. (control: Site, sponsor and IRB approvals remain required.)

## After

1. **TApp** — Re-runs eligibility searches when patient data or trial criteria change and produces candidate matches. (control: NLP match only; site capability and recency filters bound the queue.)
2. **Tempus nurse and TriHealth staff** — Nurse reviews algorithmic matches; site staff perform confirmatory screening before consent. (control: Pre-negotiated rate card/agreement and central IRB are bundled with AI; patient consent remains human.)

## Decision rights

Humans confirm eligibility and consent; AI only proposes candidates.

## Exception path

Filtered or clinically ineligible matches are discarded.

## Outcomes

- **Trial activation time** (verified): 186 days non-TIME → 37 days TIME; 80% reduction. Journal of Clinical Oncology conference supplement abstract, not a full peer-reviewed article; nonrandomized comparison and bundled operating-model change.

## Executive lesson

The unit is a human-confirmed match connected to a pre-negotiated activation lane.

## Anti-pattern

Do not attribute bundled contracting gains solely to AI.

## Questions for leaders

- Where is the operating threshold set and who can override it?
- What measured result would trigger rollback or retraining?
- Which residual decisions must remain human-owned?

## Sources

- [TriHealth collaboration with Tempus AI TIME](https://doi.org/10.1200/jco.2024.42.16_suppl.1553) — Journal of Clinical Oncology