Princess Margaret Cancer Centre / University Health Network
Verified evidenceContinuous decisioningCreator to judge
ML-assisted treatment-plan generation and blinded physician selection
A machine can generate a candidate plan, but physicians and peer review select the plan delivered.
Clinical operations · Canada
Executive brief
The operating-model shift, in one view.
Parallel human and machine plans can expose real adoption gaps that retrospective accuracy misses.
AI value · End-to-end planning time
Verified
Median 47 hours; 60.1% reduction
Single-center prospective deployment; 61% of ML plans were selected prospectively versus 83% in simulation.
Before
Manually specifies objectives and iteratively tunes a prostate radiotherapy plan. → Reviews the human-generated plan against standardized criteria.
After
Generates an ML plan in parallel with the conventional human plan. → Blindly compares candidates and selects the clinically acceptable plan for delivery.
Human boundary
Treating physicians and peer review retain final plan selection and delivery authority.
Why it matters
A machine can generate a candidate plan, but physicians and peer review select the plan delivered.
How the work changed
Before
How the work ran before the change.
Step 1 of 2
Medical dosimetrist / physicist
Manually specifies objectives and iteratively tunes a prostate radiotherapy plan.
ControlStandard planning system, dose constraints, and peer review.
Step 2 of 2
Treating physician
Reviews the human-generated plan against standardized criteria.
ControlPhysician and peer-review approval; median end-to-end baseline 118 hours.
What changed
A machine can generate a candidate plan, but physicians and peer review select the plan delivered.
Decision rightSelection moves from a fixed rule to the model
After
How the same work runs now.
Step 1 of 2
Random-forest planning system and human planner
Generates an ML plan in parallel with the conventional human plan.
ControlSame clinical criteria and standardized peer review; two independent candidate paths retained.
Step 2 of 2
Treating physician
Blindly compares candidates and selects the clinically acceptable plan for delivery.
ControlPhysician owns acceptance; unacceptable ML plans are discarded for human plans.
Process model built from the published workflow evidence for Princess Margaret Cancer Centre / University Health Network. Every step, actor, and control appears in full below.Every step, actor, and control
Exception path
An unacceptable ML plan is rejected in favor of the human-generated plan.
Decision authority
Treating physicians and peer review retain final plan selection and delivery authority.
Before
#
Actor
Action
Control
01
Medical dosimetrist / physicist
Manually specifies objectives and iteratively tunes a prostate radiotherapy plan.
Standard planning system, dose constraints, and peer review.
02
Treating physician
Reviews the human-generated plan against standardized criteria.
Physician and peer-review approval; median end-to-end baseline 118 hours.
After
#
Actor
Action
Control
01
Random-forest planning system and human planner
Generates an ML plan in parallel with the conventional human plan.
Same clinical criteria and standardized peer review; two independent candidate paths retained.
02
Treating physician
Blindly compares candidates and selects the clinically acceptable plan for delivery.
Physician owns acceptance; unacceptable ML plans are discarded for human plans.
Work that left the path
Some objective specification and iterative tuning
Human role before
Dosimetrists and physicists iteratively generate a plan for physician approval.
Human role after
Planners oversee candidate generation; physicians select and retain treatment authority.
AI role
Generates a candidate curative-intent prostate radiotherapy plan.